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Mutagenicity of bleached
and unbleached effluents from Baikalsk pulpand paper mill at
Lake Baikal, Russia
S.V. Kotelevtseva, O.O.P.
Hänninenb, P.A. Lindström-Seppä2,
S.E. Huuskonenb, L.I. Stepanovaa,
V.M. Glasera, A.M. Beimc
aBiological Department, Laboratory of
Physical Chemistry of Biomembranes, Moscow State University,
119899 Moscow, Russia.
bDepartment of Physiology, University of Kuopio, P.O.Box 1627,
FIN-70211 Kuopio, Finland.
cInstitute of Ecological Toxicology, Baikalsk, P.O.Box 48, 665914
Irkutsk region, Russia. |
Abstract
The mutagenicity of bleached pulp mill effluents was compared
to the mutagenicity of unbleached waste waters. Mutagenicity was
assessed with the Ames test, using metabolic activation systems
isolated from the liver of rats and fish. Liver extracts from fish
caught in polluted areas, and from fish experimentally exposed to
waste water, were also investigated. Pulp mill effluents, taken
after chlorination, showed mutagenic activity. The activity diminished
during the waste water treatment. Tissue extracts from fish exposed
to various concentrations of treated bleached and unbleached pulp
mill effluents showed only slight mutagenic activity in a few samples.
In the case of bleached pulp mill effluents monooxygenase activities
were elevated in those samples where slight mutagenicity was observed.
In the case of unbleached effluents no such correlation was found.
Keywords: Fish; Cytochrome P-4501A; Induction
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